P15976 (GATA1)

Overview
Predicted structure (AF):
AF-P15976-F1-model_v4
Uniprot entry:
P15976
Gene:
GATA1
Protein length:
413 residues
Mutations found:
7846
Benign based on D2Deep prediction:
3634 out of 7846 mutations
Pathogenic based on D2Deep prediction:
4212 out of 7846 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7846 mutations across 413 unique positions. There are 3634 benign and 4212 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 S 0 19 19 1.000 0.756 View mutations
252 K 0 19 19 1.000 0.683 View mutations
253 R 0 19 19 1.000 0.732 View mutations
254 A 0 19 19 1.000 0.771 View mutations
255 G 0 19 19 1.000 0.826 View mutations
256 T 0 19 19 0.990 0.802 View mutations
257 Q 0 19 19 1.000 0.749 View mutations
258 C 0 19 19 1.000 0.745 View mutations
259 T 0 19 19 0.994 0.790 View mutations
260 N 0 19 19 1.000 0.868 View mutations
261 C 0 19 19 1.000 0.913 View mutations
262 Q 0 19 19 1.000 0.743 View mutations
263 T 0 19 19 1.000 0.892 View mutations
264 T 1 18 19 0.947 0.828 View mutations
265 T 0 19 19 0.993 0.866 View mutations
266 T 0 19 19 0.997 0.901 View mutations
267 T 1 18 19 0.950 0.713 View mutations
268 L 0 19 19 0.979 0.863 View mutations
269 W 0 19 19 1.000 0.788 View mutations
270 R 0 19 19 1.000 0.870 View mutations
271 R 0 19 19 0.996 0.784 View mutations
272 N 0 19 19 0.996 0.847 View mutations
273 A 2 17 19 0.838 0.738 View mutations
274 S 2 17 19 0.899 0.766 View mutations
275 G 0 19 19 1.000 0.881 View mutations