P15976 (GATA1)

Overview
Predicted structure (AF):
AF-P15976-F1-model_v4
Uniprot entry:
P15976
Gene:
GATA1
Protein length:
413 residues
Mutations found:
7846
Benign based on D2Deep prediction:
3634 out of 7846 mutations
Pathogenic based on D2Deep prediction:
4212 out of 7846 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7846 mutations across 413 unique positions. There are 3634 benign and 4212 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 A 9 10 19 0.517 0.430 View mutations
202 R 1 18 19 0.941 0.455 View mutations
203 E 1 18 19 0.946 0.605 View mutations
204 C 2 17 19 0.859 0.524 View mutations
205 V 4 15 19 0.721 0.554 View mutations
206 N 0 19 19 0.981 0.622 View mutations
207 C 0 19 19 1.000 0.649 View mutations
208 G 0 19 19 0.999 0.719 View mutations
209 A 0 19 19 0.975 0.725 View mutations
210 T 0 19 19 0.991 0.704 View mutations
211 A 1 18 19 0.876 0.700 View mutations
212 T 0 19 19 0.999 0.723 View mutations
213 P 0 19 19 1.000 0.690 View mutations
214 L 0 19 19 1.000 0.643 View mutations
215 W 0 19 19 0.993 0.646 View mutations
216 R 0 19 19 1.000 0.615 View mutations
217 R 1 18 19 0.947 0.591 View mutations
218 D 1 18 19 0.961 0.617 View mutations
219 R 7 12 19 0.586 0.442 View mutations
220 T 4 15 19 0.743 0.605 View mutations
221 G 0 19 19 0.975 0.660 View mutations
222 H 6 13 19 0.673 0.564 View mutations
223 Y 6 13 19 0.698 0.566 View mutations
224 L 0 19 19 0.967 0.860 View mutations
225 C 0 19 19 1.000 0.777 View mutations