P15976 (GATA1)

Overview
Predicted structure (AF):
AF-P15976-F1-model_v4
Uniprot entry:
P15976
Gene:
GATA1
Protein length:
413 residues
Mutations found:
7846
Benign based on D2Deep prediction:
3634 out of 7846 mutations
Pathogenic based on D2Deep prediction:
4212 out of 7846 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7846 mutations across 413 unique positions. There are 3634 benign and 4212 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 T 18 1 19 0.068 0.508 View mutations
177 G 18 1 19 0.103 0.420 View mutations
178 S 19 0 19 0.063 0.527 View mutations
179 P 19 0 19 0.052 0.457 View mutations
180 L 19 0 19 0.039 0.549 View mutations
181 N 19 0 19 0.004 0.653 View mutations
182 S 19 0 19 0.059 0.655 View mutations
183 A 18 1 19 0.107 0.598 View mutations
184 A 19 0 19 0.033 0.655 View mutations
185 Y 18 1 19 0.106 0.625 View mutations
186 S 19 0 19 0.033 0.603 View mutations
187 S 14 5 19 0.299 0.503 View mutations
188 P 11 8 19 0.414 0.437 View mutations
189 K 6 13 19 0.642 0.423 View mutations
190 L 10 9 19 0.462 0.445 View mutations
191 R 9 10 19 0.496 0.443 View mutations
192 G 9 10 19 0.549 0.436 View mutations
193 T 13 6 19 0.360 0.518 View mutations
194 L 10 9 19 0.481 0.450 View mutations
195 P 14 5 19 0.379 0.526 View mutations
196 L 13 6 19 0.298 0.510 View mutations
197 P 12 7 19 0.382 0.504 View mutations
198 P 11 8 19 0.443 0.472 View mutations
199 C 8 11 19 0.621 0.430 View mutations
200 E 0 19 19 0.984 0.469 View mutations