P15976 (GATA1)

Overview
Predicted structure (AF):
AF-P15976-F1-model_v4
Uniprot entry:
P15976
Gene:
GATA1
Protein length:
413 residues
Mutations found:
7846
Benign based on D2Deep prediction:
3634 out of 7846 mutations
Pathogenic based on D2Deep prediction:
4212 out of 7846 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7846 mutations across 413 unique positions. There are 3634 benign and 4212 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 G 12 7 19 0.439 0.383 View mutations
302 I 6 13 19 0.660 0.661 View mutations
303 Q 4 15 19 0.713 0.662 View mutations
304 T 11 8 19 0.451 0.449 View mutations
305 R 1 18 19 0.816 0.764 View mutations
306 N 1 18 19 0.892 0.746 View mutations
307 R 1 18 19 0.945 0.728 View mutations
308 K 13 6 19 0.346 0.419 View mutations
309 A 13 6 19 0.294 0.393 View mutations
310 S 12 7 19 0.370 0.450 View mutations
311 G 11 8 19 0.425 0.476 View mutations
312 K 16 3 19 0.142 0.400 View mutations
313 G 19 0 19 0.039 0.404 View mutations
314 K 15 4 19 0.385 0.460 View mutations
315 K 13 6 19 0.400 0.470 View mutations
316 K 19 0 19 0.029 0.474 View mutations
317 R 18 1 19 0.136 0.460 View mutations
318 G 18 1 19 0.072 0.527 View mutations
319 S 19 0 19 0.038 0.572 View mutations
320 S 19 0 19 0.015 0.618 View mutations
321 L 17 2 19 0.145 0.548 View mutations
322 G 19 0 19 0.054 0.745 View mutations
323 G 18 1 19 0.056 0.788 View mutations
324 T 6 13 19 0.603 0.337 View mutations
325 G 6 13 19 0.615 0.345 View mutations