P15976 (GATA1)

Overview
Predicted structure (AF):
AF-P15976-F1-model_v4
Uniprot entry:
P15976
Gene:
GATA1
Protein length:
413 residues
Mutations found:
7846
Benign based on D2Deep prediction:
3634 out of 7846 mutations
Pathogenic based on D2Deep prediction:
4212 out of 7846 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7846 mutations across 413 unique positions. There are 3634 benign and 4212 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
326 A 13 6 19 0.287 0.648 View mutations
327 A 16 3 19 0.153 0.753 View mutations
328 E 1 18 19 0.898 0.208 View mutations
329 G 16 3 19 0.178 0.734 View mutations
330 P 11 8 19 0.438 0.551 View mutations
331 A 6 13 19 0.715 0.342 View mutations
332 G 8 11 19 0.587 0.426 View mutations
333 G 14 5 19 0.295 0.571 View mutations
334 F 1 18 19 0.943 0.313 View mutations
335 M 11 8 19 0.371 0.501 View mutations
336 V 8 11 19 0.578 0.429 View mutations
337 V 14 5 19 0.270 0.553 View mutations
338 A 16 3 19 0.185 0.654 View mutations
339 G 16 3 19 0.159 0.670 View mutations
340 G 16 3 19 0.207 0.713 View mutations
341 S 17 2 19 0.094 0.781 View mutations
342 G 19 0 19 0.075 0.779 View mutations
343 S 10 9 19 0.478 0.486 View mutations
344 G 3 16 19 0.856 0.313 View mutations
345 N 15 4 19 0.204 0.597 View mutations
346 C 16 3 19 0.149 0.659 View mutations
347 G 10 9 19 0.496 0.476 View mutations
348 E 11 8 19 0.380 0.484 View mutations
349 V 16 3 19 0.175 0.622 View mutations
350 A 18 1 19 0.120 0.677 View mutations