P15976 (GATA1)

Overview
Predicted structure (AF):
AF-P15976-F1-model_v4
Uniprot entry:
P15976
Gene:
GATA1
Protein length:
413 residues
Mutations found:
7846
Benign based on D2Deep prediction:
3634 out of 7846 mutations
Pathogenic based on D2Deep prediction:
4212 out of 7846 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7846 mutations across 413 unique positions. There are 3634 benign and 4212 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 G 13 6 19 0.401 0.464 View mutations
127 K 10 9 19 0.474 0.451 View mutations
128 G 2 17 19 0.794 0.320 View mutations
129 S 11 8 19 0.431 0.499 View mutations
130 T 3 16 19 0.816 0.311 View mutations
131 S 2 17 19 0.830 0.368 View mutations
132 F 0 19 19 0.974 0.459 View mutations
133 L 1 18 19 0.895 0.490 View mutations
134 E 1 18 19 0.940 0.531 View mutations
135 T 6 13 19 0.705 0.530 View mutations
136 L 2 17 19 0.878 0.565 View mutations
137 K 5 14 19 0.620 0.535 View mutations
138 T 6 13 19 0.654 0.529 View mutations
139 E 1 18 19 0.743 0.607 View mutations
140 R 2 17 19 0.709 0.464 View mutations
141 L 14 5 19 0.351 0.497 View mutations
142 S 15 4 19 0.241 0.494 View mutations
143 P 17 2 19 0.175 0.432 View mutations
144 D 19 0 19 0.059 0.392 View mutations
145 L 19 0 19 0.049 0.367 View mutations
146 L 19 0 19 0.013 0.386 View mutations
147 T 19 0 19 0.048 0.402 View mutations
148 L 19 0 19 0.014 0.451 View mutations
149 G 18 1 19 0.107 0.411 View mutations
150 P 19 0 19 0.019 0.689 View mutations