P15976 (GATA1)

Overview
Predicted structure (AF):
AF-P15976-F1-model_v4
Uniprot entry:
P15976
Gene:
GATA1
Protein length:
413 residues
Mutations found:
7846
Benign based on D2Deep prediction:
3634 out of 7846 mutations
Pathogenic based on D2Deep prediction:
4212 out of 7846 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7846 mutations across 413 unique positions. There are 3634 benign and 4212 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 A 18 1 19 0.062 0.549 View mutations
152 L 12 7 19 0.403 0.510 View mutations
153 P 18 1 19 0.074 0.555 View mutations
154 S 19 0 19 0.013 0.609 View mutations
155 S 18 1 19 0.093 0.549 View mutations
156 L 13 6 19 0.389 0.516 View mutations
157 P 18 1 19 0.087 0.633 View mutations
158 V 11 8 19 0.412 0.479 View mutations
159 P 15 4 19 0.261 0.598 View mutations
160 N 14 5 19 0.248 0.574 View mutations
161 S 18 1 19 0.082 0.662 View mutations
162 A 5 14 19 0.701 0.394 View mutations
163 Y 0 19 19 0.957 0.360 View mutations
164 G 17 2 19 0.183 0.452 View mutations
165 G 19 0 19 0.013 0.597 View mutations
166 P 18 1 19 0.103 0.569 View mutations
167 D 18 1 19 0.075 0.404 View mutations
168 F 18 1 19 0.168 0.537 View mutations
169 S 18 1 19 0.055 0.651 View mutations
170 S 19 0 19 0.032 0.712 View mutations
171 T 16 3 19 0.197 0.562 View mutations
172 F 11 8 19 0.437 0.467 View mutations
173 F 19 0 19 0.022 0.639 View mutations
174 S 19 0 19 0.034 0.653 View mutations
175 P 18 1 19 0.041 0.497 View mutations