P16410 (CTLA4)

Overview
Predicted structure (AF):
AF-P16410-F1-model_v4
Uniprot entry:
P16410
Gene:
CTLA4
Protein length:
223 residues
Mutations found:
4236
Benign based on D2Deep prediction:
2742 out of 4236 mutations
Pathogenic based on D2Deep prediction:
1494 out of 4236 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4236 mutations across 223 unique positions. There are 2742 benign and 1494 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 S 19 0 19 0.002 0.593 View mutations
102 I 16 3 19 0.154 0.538 View mutations
103 C 18 1 19 0.175 0.387 View mutations
104 T 10 9 19 0.507 0.447 View mutations
105 G 15 4 19 0.265 0.438 View mutations
106 T 19 0 19 0.043 0.611 View mutations
107 S 19 0 19 0.000 0.469 View mutations
108 S 19 0 19 0.007 0.577 View mutations
109 G 19 0 19 0.000 0.464 View mutations
110 N 19 0 19 0.000 0.354 View mutations
111 Q 19 0 19 0.000 0.474 View mutations
112 V 19 0 19 0.028 0.371 View mutations
113 N 19 0 19 0.032 0.424 View mutations
114 L 19 0 19 0.077 0.188 View mutations
115 T 18 1 19 0.136 0.359 View mutations
116 I 18 1 19 0.088 0.337 View mutations
117 Q 7 12 19 0.613 0.520 View mutations
118 G 18 1 19 0.174 0.342 View mutations
119 L 4 15 19 0.735 0.630 View mutations
120 R 15 4 19 0.321 0.433 View mutations
121 A 3 16 19 0.776 0.557 View mutations
122 M 18 1 19 0.110 0.404 View mutations
123 D 0 19 19 0.938 0.669 View mutations
124 T 12 7 19 0.384 0.464 View mutations
125 G 0 19 19 0.894 0.826 View mutations