P16422 (EPCAM)

Overview
Predicted structure (AF):
AF-P16422-F1-model_v4
Uniprot entry:
P16422
Gene:
EPCAM
Protein length:
314 residues
Mutations found:
5965
Benign based on D2Deep prediction:
3951 out of 5965 mutations
Pathogenic based on D2Deep prediction:
2014 out of 5965 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5965 mutations across 314 unique positions. There are 3951 benign and 2014 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 L 12 7 19 0.398 0.433 View mutations
177 D 18 1 19 0.114 0.611 View mutations
178 P 19 0 19 0.032 0.589 View mutations
179 K 18 1 19 0.078 0.527 View mutations
180 F 7 12 19 0.623 0.433 View mutations
181 I 19 0 19 0.000 0.454 View mutations
182 T 19 0 19 0.001 0.673 View mutations
183 S 19 0 19 0.036 0.618 View mutations
184 I 19 0 19 0.001 0.456 View mutations
185 L 19 0 19 0.004 0.483 View mutations
186 Y 19 0 19 0.024 0.424 View mutations
187 E 13 6 19 0.346 0.446 View mutations
188 N 17 2 19 0.116 0.482 View mutations
189 N 14 5 19 0.361 0.423 View mutations
190 V 15 4 19 0.186 0.503 View mutations
191 I 2 17 19 0.858 0.579 View mutations
192 T 18 1 19 0.066 0.441 View mutations
193 I 5 14 19 0.722 0.571 View mutations
194 D 18 1 19 0.136 0.431 View mutations
195 L 7 12 19 0.648 0.538 View mutations
196 V 19 0 19 0.006 0.434 View mutations
197 Q 18 1 19 0.103 0.428 View mutations
198 N 0 19 19 0.995 0.515 View mutations
199 S 16 3 19 0.155 0.388 View mutations
200 S 1 18 19 0.937 0.478 View mutations