P16422 (EPCAM)

Overview
Predicted structure (AF):
AF-P16422-F1-model_v4
Uniprot entry:
P16422
Gene:
EPCAM
Protein length:
314 residues
Mutations found:
5965
Benign based on D2Deep prediction:
3951 out of 5965 mutations
Pathogenic based on D2Deep prediction:
2014 out of 5965 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5965 mutations across 314 unique positions. There are 3951 benign and 2014 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 Q 9 10 19 0.495 0.440 View mutations
202 K 19 0 19 0.013 0.529 View mutations
203 T 19 0 19 0.002 0.480 View mutations
204 Q 17 2 19 0.126 0.521 View mutations
205 N 13 6 19 0.289 0.448 View mutations
206 D 4 15 19 0.798 0.542 View mutations
207 V 2 17 19 0.897 0.617 View mutations
208 D 10 9 19 0.539 0.493 View mutations
209 I 8 11 19 0.461 0.530 View mutations
210 A 19 0 19 0.029 0.307 View mutations
211 D 13 6 19 0.346 0.408 View mutations
212 V 0 19 19 0.982 0.685 View mutations
213 A 3 16 19 0.782 0.661 View mutations
214 Y 0 19 19 0.949 0.708 View mutations
215 Y 10 9 19 0.491 0.491 View mutations
216 F 0 19 19 0.984 0.685 View mutations
217 E 7 12 19 0.638 0.564 View mutations
218 K 8 11 19 0.568 0.505 View mutations
219 D 9 10 19 0.591 0.502 View mutations
220 V 19 0 19 0.015 0.380 View mutations
221 K 19 0 19 0.001 0.357 View mutations
222 G 16 3 19 0.298 0.419 View mutations
223 E 19 0 19 0.025 0.455 View mutations
224 S 18 1 19 0.087 0.455 View mutations
225 L 19 0 19 0.096 0.441 View mutations