P16422 (EPCAM)

Overview
Predicted structure (AF):
AF-P16422-F1-model_v4
Uniprot entry:
P16422
Gene:
EPCAM
Protein length:
314 residues
Mutations found:
5965
Benign based on D2Deep prediction:
3951 out of 5965 mutations
Pathogenic based on D2Deep prediction:
2014 out of 5965 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5965 mutations across 314 unique positions. There are 3951 benign and 2014 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 R 1 18 19 0.943 0.802 View mutations
127 T 0 19 19 0.998 0.786 View mutations
128 D 3 16 19 0.833 0.600 View mutations
129 K 4 15 19 0.801 0.530 View mutations
130 D 2 17 19 0.816 0.541 View mutations
131 T 1 18 19 0.917 0.453 View mutations
132 E 3 16 19 0.715 0.429 View mutations
133 I 11 8 19 0.407 0.488 View mutations
134 T 14 5 19 0.238 0.487 View mutations
135 C 0 19 19 0.999 0.670 View mutations
136 S 16 3 19 0.206 0.495 View mutations
137 E 17 2 19 0.227 0.447 View mutations
138 R 18 1 19 0.076 0.431 View mutations
139 V 17 2 19 0.171 0.377 View mutations
140 R 2 17 19 0.823 0.559 View mutations
141 T 15 4 19 0.303 0.456 View mutations
142 Y 19 0 19 0.009 0.362 View mutations
143 W 19 0 19 0.001 0.385 View mutations
144 I 17 2 19 0.159 0.378 View mutations
145 I 19 0 19 0.002 0.396 View mutations
146 I 19 0 19 0.000 0.394 View mutations
147 E 10 9 19 0.438 0.444 View mutations
148 L 19 0 19 0.000 0.368 View mutations
149 K 19 0 19 0.028 0.541 View mutations
150 H 19 0 19 0.000 0.487 View mutations