P16422 (EPCAM)

Overview
Predicted structure (AF):
AF-P16422-F1-model_v4
Uniprot entry:
P16422
Gene:
EPCAM
Protein length:
314 residues
Mutations found:
5965
Benign based on D2Deep prediction:
3951 out of 5965 mutations
Pathogenic based on D2Deep prediction:
2014 out of 5965 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5965 mutations across 314 unique positions. There are 3951 benign and 2014 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 K 19 0 19 0.000 0.581 View mutations
152 A 11 8 19 0.410 0.474 View mutations
153 R 18 1 19 0.112 0.623 View mutations
154 E 19 0 19 0.001 0.654 View mutations
155 K 18 1 19 0.082 0.671 View mutations
156 P 19 0 19 0.001 0.465 View mutations
157 Y 19 0 19 0.003 0.547 View mutations
158 D 18 1 19 0.029 0.608 View mutations
159 S 19 0 19 0.002 0.585 View mutations
160 K 19 0 19 0.001 0.679 View mutations
161 S 19 0 19 0.016 0.594 View mutations
162 L 12 7 19 0.428 0.442 View mutations
163 R 18 1 19 0.058 0.622 View mutations
164 T 17 2 19 0.087 0.663 View mutations
165 A 19 0 19 0.006 0.574 View mutations
166 L 12 7 19 0.464 0.497 View mutations
167 Q 19 0 19 0.000 0.653 View mutations
168 K 19 0 19 0.005 0.680 View mutations
169 E 17 2 19 0.156 0.597 View mutations
170 I 18 1 19 0.140 0.442 View mutations
171 T 19 0 19 0.013 0.678 View mutations
172 T 19 0 19 0.044 0.574 View mutations
173 R 19 0 19 0.010 0.362 View mutations
174 Y 16 3 19 0.211 0.388 View mutations
175 Q 19 0 19 0.004 0.563 View mutations