P23771-2 (GATA3)

Overview
Predicted structure (AF):
AF-P23771-2-F1-model_v4
Uniprot entry:
P23771-2
Gene:
GATA3
Protein length:
444 residues
Mutations found:
8435
Benign based on D2Deep prediction:
3875 out of 8435 mutations
Pathogenic based on D2Deep prediction:
4560 out of 8435 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8435 mutations across 444 unique positions. There are 3875 benign and 4560 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 V 13 6 19 0.313 0.555 View mutations
227 P 19 0 19 0.000 0.726 View mutations
228 E 4 15 19 0.818 0.391 View mutations
229 Y 0 19 19 0.999 0.274 View mutations
230 S 8 11 19 0.563 0.431 View mutations
231 S 10 9 19 0.459 0.470 View mutations
232 G 3 16 19 0.815 0.367 View mutations
233 L 0 19 19 1.000 0.322 View mutations
234 F 0 19 19 1.000 0.314 View mutations
235 P 11 8 19 0.398 0.481 View mutations
236 P 19 0 19 0.010 0.595 View mutations
237 S 4 15 19 0.720 0.361 View mutations
238 S 2 17 19 0.876 0.328 View mutations
239 L 4 15 19 0.752 0.369 View mutations
240 L 11 8 19 0.393 0.487 View mutations
241 G 17 2 19 0.151 0.676 View mutations
242 G 12 7 19 0.393 0.524 View mutations
243 S 14 5 19 0.311 0.616 View mutations
244 P 19 0 19 0.013 0.835 View mutations
245 T 14 5 19 0.334 0.665 View mutations
246 G 18 1 19 0.071 0.758 View mutations
247 F 19 0 19 0.005 0.712 View mutations
248 G 9 10 19 0.538 0.463 View mutations
249 C 9 10 19 0.503 0.464 View mutations
250 K 1 18 19 0.933 0.243 View mutations