P23771-2 (GATA3)

Overview
Predicted structure (AF):
AF-P23771-2-F1-model_v4
Uniprot entry:
P23771-2
Gene:
GATA3
Protein length:
444 residues
Mutations found:
8435
Benign based on D2Deep prediction:
3875 out of 8435 mutations
Pathogenic based on D2Deep prediction:
4560 out of 8435 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8435 mutations across 444 unique positions. There are 3875 benign and 4560 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 S 15 4 19 0.208 0.681 View mutations
252 R 2 17 19 0.887 0.264 View mutations
253 P 4 15 19 0.749 0.319 View mutations
254 K 9 10 19 0.550 0.450 View mutations
255 A 13 6 19 0.330 0.571 View mutations
256 R 1 18 19 0.953 0.267 View mutations
257 S 4 15 19 0.718 0.326 View mutations
258 S 12 7 19 0.450 0.531 View mutations
259 T 11 8 19 0.458 0.505 View mutations
260 E 18 1 19 0.073 0.528 View mutations
261 G 0 19 19 1.000 0.428 View mutations
262 R 0 19 19 1.000 0.489 View mutations
263 E 1 18 19 0.932 0.533 View mutations
264 C 2 17 19 0.869 0.482 View mutations
265 V 4 15 19 0.789 0.552 View mutations
266 N 4 15 19 0.813 0.527 View mutations
267 C 0 19 19 1.000 0.518 View mutations
268 G 0 19 19 0.996 0.590 View mutations
269 A 0 19 19 0.997 0.567 View mutations
270 T 0 19 19 1.000 0.509 View mutations
271 S 1 18 19 0.949 0.469 View mutations
272 T 2 17 19 0.894 0.503 View mutations
273 P 1 18 19 0.968 0.519 View mutations
274 L 0 19 19 0.997 0.532 View mutations
275 W 1 18 19 0.943 0.419 View mutations