P23771-2 (GATA3)

Overview
Predicted structure (AF):
AF-P23771-2-F1-model_v4
Uniprot entry:
P23771-2
Gene:
GATA3
Protein length:
444 residues
Mutations found:
8435
Benign based on D2Deep prediction:
3875 out of 8435 mutations
Pathogenic based on D2Deep prediction:
4560 out of 8435 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8435 mutations across 444 unique positions. There are 3875 benign and 4560 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 R 0 19 19 1.000 0.498 View mutations
277 R 2 17 19 0.851 0.478 View mutations
278 D 1 18 19 0.948 0.413 View mutations
279 G 5 14 19 0.673 0.419 View mutations
280 T 2 17 19 0.848 0.504 View mutations
281 G 0 19 19 1.000 0.533 View mutations
282 H 0 19 19 1.000 0.515 View mutations
283 Y 0 19 19 1.000 0.534 View mutations
284 L 0 19 19 1.000 0.549 View mutations
285 C 0 19 19 1.000 0.506 View mutations
286 N 6 13 19 0.668 0.513 View mutations
287 A 6 13 19 0.715 0.522 View mutations
288 C 1 18 19 0.960 0.537 View mutations
289 G 2 17 19 0.925 0.522 View mutations
290 L 0 19 19 0.999 0.609 View mutations
291 Y 1 18 19 0.943 0.538 View mutations
292 H 0 19 19 0.980 0.501 View mutations
293 K 1 18 19 0.946 0.509 View mutations
294 M 0 19 19 0.987 0.517 View mutations
295 N 5 14 19 0.726 0.522 View mutations
296 G 8 11 19 0.605 0.513 View mutations
297 Q 1 18 19 0.965 0.504 View mutations
298 N 0 19 19 1.000 0.537 View mutations
299 R 1 18 19 0.966 0.556 View mutations
300 P 0 19 19 0.990 0.644 View mutations