P23771-2 (GATA3)

Overview
Predicted structure (AF):
AF-P23771-2-F1-model_v4
Uniprot entry:
P23771-2
Gene:
GATA3
Protein length:
444 residues
Mutations found:
8435
Benign based on D2Deep prediction:
3875 out of 8435 mutations
Pathogenic based on D2Deep prediction:
4560 out of 8435 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8435 mutations across 444 unique positions. There are 3875 benign and 4560 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 S 15 4 19 0.236 0.653 View mutations
202 R 19 0 19 0.047 0.747 View mutations
203 G 19 0 19 0.000 0.863 View mutations
204 S 19 0 19 0.001 0.937 View mutations
205 M 18 1 19 0.044 0.854 View mutations
206 T 17 2 19 0.094 0.817 View mutations
207 A 19 0 19 0.026 0.904 View mutations
208 L 18 1 19 0.033 0.863 View mutations
209 G 19 0 19 0.028 0.894 View mutations
210 G 16 3 19 0.179 0.784 View mutations
211 A 17 2 19 0.132 0.846 View mutations
212 S 8 11 19 0.557 0.424 View mutations
213 S 5 14 19 0.614 0.305 View mutations
214 S 9 10 19 0.541 0.463 View mutations
215 T 15 4 19 0.197 0.637 View mutations
216 H 0 19 19 0.925 0.361 View mutations
217 H 9 10 19 0.475 0.444 View mutations
218 P 14 5 19 0.309 0.491 View mutations
219 I 19 0 19 0.007 0.581 View mutations
220 T 19 0 19 0.002 0.589 View mutations
221 T 18 1 19 0.030 0.575 View mutations
222 Y 15 4 19 0.245 0.523 View mutations
223 P 19 0 19 0.001 0.606 View mutations
224 P 18 1 19 0.095 0.650 View mutations
225 Y 16 3 19 0.151 0.581 View mutations