P23771-2 (GATA3)

Overview
Predicted structure (AF):
AF-P23771-2-F1-model_v4
Uniprot entry:
P23771-2
Gene:
GATA3
Protein length:
444 residues
Mutations found:
8435
Benign based on D2Deep prediction:
3875 out of 8435 mutations
Pathogenic based on D2Deep prediction:
4560 out of 8435 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8435 mutations across 444 unique positions. There are 3875 benign and 4560 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 A 19 0 19 0.004 0.868 View mutations
177 R 18 1 19 0.102 0.719 View mutations
178 Q 19 0 19 0.001 0.750 View mutations
179 D 18 1 19 0.087 0.625 View mutations
180 E 9 10 19 0.596 0.444 View mutations
181 K 16 3 19 0.264 0.524 View mutations
182 E 17 2 19 0.230 0.532 View mutations
183 C 16 3 19 0.191 0.606 View mutations
184 L 10 9 19 0.465 0.460 View mutations
185 K 19 0 19 0.029 0.575 View mutations
186 Y 19 0 19 0.029 0.602 View mutations
187 Q 11 8 19 0.312 0.505 View mutations
188 V 18 1 19 0.069 0.698 View mutations
189 P 13 6 19 0.304 0.573 View mutations
190 L 17 2 19 0.102 0.645 View mutations
191 P 14 5 19 0.268 0.590 View mutations
192 D 17 2 19 0.151 0.592 View mutations
193 S 18 1 19 0.094 0.632 View mutations
194 M 3 16 19 0.844 0.376 View mutations
195 K 10 9 19 0.468 0.457 View mutations
196 L 19 0 19 0.012 0.630 View mutations
197 E 18 1 19 0.072 0.526 View mutations
198 S 14 5 19 0.282 0.593 View mutations
199 S 17 2 19 0.113 0.732 View mutations
200 H 5 14 19 0.682 0.338 View mutations