P23771-2 (GATA3)

Overview
Predicted structure (AF):
AF-P23771-2-F1-model_v4
Uniprot entry:
P23771-2
Gene:
GATA3
Protein length:
444 residues
Mutations found:
8435
Benign based on D2Deep prediction:
3875 out of 8435 mutations
Pathogenic based on D2Deep prediction:
4560 out of 8435 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8435 mutations across 444 unique positions. There are 3875 benign and 4560 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 L 4 15 19 0.756 0.541 View mutations
302 I 4 15 19 0.755 0.541 View mutations
303 K 1 18 19 0.949 0.511 View mutations
304 P 0 19 19 0.998 0.534 View mutations
305 K 14 5 19 0.261 0.405 View mutations
306 R 2 17 19 0.883 0.474 View mutations
307 R 1 18 19 0.921 0.512 View mutations
308 L 15 4 19 0.288 0.402 View mutations
309 S 18 1 19 0.056 0.433 View mutations
310 A 11 8 19 0.419 0.481 View mutations
311 A 11 8 19 0.407 0.478 View mutations
312 R 18 1 19 0.062 0.339 View mutations
313 R 17 2 19 0.145 0.332 View mutations
314 A 1 18 19 0.960 0.683 View mutations
315 G 0 19 19 1.000 0.761 View mutations
316 T 11 8 19 0.412 0.460 View mutations
317 S 8 11 19 0.579 0.533 View mutations
318 C 15 4 19 0.219 0.347 View mutations
319 A 12 7 19 0.408 0.416 View mutations
320 N 4 15 19 0.762 0.672 View mutations
321 C 4 15 19 0.768 0.675 View mutations
322 Q 0 19 19 0.999 0.721 View mutations
323 T 0 19 19 0.999 0.855 View mutations
324 T 1 18 19 0.970 0.756 View mutations
325 T 0 19 19 0.977 0.734 View mutations