P23771-2 (GATA3)

Overview
Predicted structure (AF):
AF-P23771-2-F1-model_v4
Uniprot entry:
P23771-2
Gene:
GATA3
Protein length:
444 residues
Mutations found:
8435
Benign based on D2Deep prediction:
3875 out of 8435 mutations
Pathogenic based on D2Deep prediction:
4560 out of 8435 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8435 mutations across 444 unique positions. There are 3875 benign and 4560 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 S 12 7 19 0.321 0.562 View mutations
127 P 2 17 19 0.856 0.284 View mutations
128 G 2 17 19 0.884 0.260 View mutations
129 P 12 7 19 0.304 0.548 View mutations
130 L 2 17 19 0.902 0.249 View mutations
131 S 3 16 19 0.826 0.323 View mutations
132 V 3 16 19 0.723 0.323 View mutations
133 Y 10 9 19 0.433 0.472 View mutations
134 P 4 15 19 0.750 0.352 View mutations
135 P 18 1 19 0.052 0.727 View mutations
136 A 16 3 19 0.156 0.663 View mutations
137 S 14 5 19 0.262 0.600 View mutations
138 S 13 6 19 0.318 0.595 View mutations
139 S 16 3 19 0.178 0.700 View mutations
140 S 15 4 19 0.252 0.674 View mutations
141 L 16 3 19 0.161 0.743 View mutations
142 S 19 0 19 0.021 0.828 View mutations
143 G 19 0 19 0.001 0.808 View mutations
144 G 19 0 19 0.036 0.736 View mutations
145 H 19 0 19 0.024 0.665 View mutations
146 A 19 0 19 0.005 0.675 View mutations
147 S 18 1 19 0.101 0.643 View mutations
148 P 19 0 19 0.009 0.544 View mutations
149 H 17 2 19 0.133 0.524 View mutations
150 L 19 0 19 0.003 0.523 View mutations