P23771-2 (GATA3)

Overview
Predicted structure (AF):
AF-P23771-2-F1-model_v4
Uniprot entry:
P23771-2
Gene:
GATA3
Protein length:
444 residues
Mutations found:
8435
Benign based on D2Deep prediction:
3875 out of 8435 mutations
Pathogenic based on D2Deep prediction:
4560 out of 8435 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8435 mutations across 444 unique positions. There are 3875 benign and 4560 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 F 12 7 19 0.380 0.465 View mutations
152 T 6 13 19 0.700 0.428 View mutations
153 F 3 16 19 0.842 0.466 View mutations
154 P 1 18 19 0.930 0.518 View mutations
155 P 0 19 19 1.000 0.557 View mutations
156 T 0 19 19 0.999 0.515 View mutations
157 P 0 19 19 1.000 0.615 View mutations
158 P 0 19 19 1.000 0.613 View mutations
159 K 1 18 19 0.948 0.454 View mutations
160 D 1 18 19 0.943 0.546 View mutations
161 V 3 16 19 0.825 0.532 View mutations
162 S 0 19 19 1.000 0.448 View mutations
163 P 0 19 19 1.000 0.446 View mutations
164 D 1 18 19 0.946 0.441 View mutations
165 P 14 5 19 0.230 0.553 View mutations
166 S 12 7 19 0.395 0.565 View mutations
167 L 18 1 19 0.058 0.764 View mutations
168 S 18 1 19 0.078 0.755 View mutations
169 T 17 2 19 0.093 0.740 View mutations
170 P 19 0 19 0.028 0.787 View mutations
171 G 15 4 19 0.254 0.709 View mutations
172 S 19 0 19 0.002 1.000 View mutations
173 A 19 0 19 0.001 0.996 View mutations
174 G 19 0 19 0.001 0.976 View mutations
175 S 19 0 19 0.007 0.959 View mutations