P25445 (P25445)

Overview
Predicted structure (AF):
AF-P25445-F1-model_v4
Uniprot entry:
P25445
Gene:
P25445
Protein length:
335 residues
Mutations found:
6364
Benign based on D2Deep prediction:
4666 out of 6364 mutations
Pathogenic based on D2Deep prediction:
1698 out of 6364 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 6364 mutations across 335 unique positions. There are 4666 benign and 1698 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 K 1 18 19 0.920 0.716 View mutations
127 C 17 2 19 0.277 0.229 View mutations
128 R 0 19 19 1.000 0.894 View mutations
129 C 18 1 19 0.132 0.203 View mutations
130 K 5 14 19 0.705 0.630 View mutations
131 P 4 15 19 0.802 0.606 View mutations
132 N 1 18 19 0.919 0.755 View mutations
133 F 19 0 19 0.022 0.160 View mutations
134 F 3 16 19 0.802 0.697 View mutations
135 C 1 18 19 0.932 0.733 View mutations
136 N 10 9 19 0.442 0.500 View mutations
137 S 15 4 19 0.274 0.475 View mutations
138 T 18 1 19 0.072 0.413 View mutations
139 V 19 0 19 0.004 0.344 View mutations
140 C 0 19 19 0.800 0.794 View mutations
141 E 19 0 19 0.046 0.194 View mutations
142 H 19 0 19 0.019 0.239 View mutations
143 C 19 0 19 0.000 0.145 View mutations
144 D 19 0 19 0.002 0.391 View mutations
145 P 18 1 19 0.046 0.255 View mutations
146 C 17 2 19 0.227 0.320 View mutations
147 T 16 3 19 0.187 0.438 View mutations
148 K 19 0 19 0.000 0.457 View mutations
149 C 19 0 19 0.005 0.305 View mutations
150 E 19 0 19 0.000 0.401 View mutations