P25445 (P25445)

Overview
Predicted structure (AF):
AF-P25445-F1-model_v4
Uniprot entry:
P25445
Gene:
P25445
Protein length:
335 residues
Mutations found:
6364
Benign based on D2Deep prediction:
4666 out of 6364 mutations
Pathogenic based on D2Deep prediction:
1698 out of 6364 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 6364 mutations across 335 unique positions. There are 4666 benign and 1698 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 C 19 0 19 0.012 0.198 View mutations
102 R 15 4 19 0.260 0.362 View mutations
103 R 9 10 19 0.544 0.511 View mutations
104 C 0 19 19 0.905 0.784 View mutations
105 R 12 7 19 0.406 0.465 View mutations
106 L 18 1 19 0.072 0.351 View mutations
107 C 12 7 19 0.380 0.427 View mutations
108 D 19 0 19 0.043 0.272 View mutations
109 E 19 0 19 0.016 0.283 View mutations
110 G 19 0 19 0.005 0.268 View mutations
111 H 19 0 19 0.061 0.255 View mutations
112 G 19 0 19 0.016 0.073 View mutations
113 L 18 1 19 0.092 0.162 View mutations
114 E 19 0 19 0.042 0.129 View mutations
115 V 14 5 19 0.306 0.345 View mutations
116 E 3 16 19 0.769 0.690 View mutations
117 I 11 8 19 0.417 0.476 View mutations
118 N 14 5 19 0.359 0.411 View mutations
119 C 2 17 19 0.846 0.755 View mutations
120 T 17 2 19 0.160 0.293 View mutations
121 R 5 14 19 0.740 0.559 View mutations
122 T 18 1 19 0.086 0.319 View mutations
123 Q 11 8 19 0.435 0.455 View mutations
124 N 1 18 19 0.927 0.808 View mutations
125 T 3 16 19 0.838 0.747 View mutations