P25445 (P25445)

Overview
Predicted structure (AF):
AF-P25445-F1-model_v4
Uniprot entry:
P25445
Gene:
P25445
Protein length:
335 residues
Mutations found:
6364
Benign based on D2Deep prediction:
4666 out of 6364 mutations
Pathogenic based on D2Deep prediction:
1698 out of 6364 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 6364 mutations across 335 unique positions. There are 4666 benign and 1698 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 H 15 4 19 0.212 0.461 View mutations
152 G 9 10 19 0.569 0.508 View mutations
153 I 14 5 19 0.248 0.436 View mutations
154 I 17 2 19 0.160 0.453 View mutations
155 K 3 16 19 0.761 0.560 View mutations
156 E 14 5 19 0.311 0.491 View mutations
157 C 0 19 19 0.996 0.648 View mutations
158 T 4 15 19 0.716 0.577 View mutations
159 L 17 2 19 0.146 0.407 View mutations
160 T 17 2 19 0.113 0.403 View mutations
161 S 14 5 19 0.328 0.462 View mutations
162 N 2 17 19 0.900 0.578 View mutations
163 T 7 12 19 0.624 0.533 View mutations
164 K 9 10 19 0.495 0.502 View mutations
165 C 0 19 19 0.935 0.577 View mutations
166 K 19 0 19 0.094 0.530 View mutations
167 E 18 1 19 0.031 0.618 View mutations
168 E 19 0 19 0.039 0.677 View mutations
169 G 19 0 19 0.021 0.634 View mutations
170 S 19 0 19 0.000 0.802 View mutations
171 R 19 0 19 0.006 0.808 View mutations
172 S 19 0 19 0.001 0.885 View mutations
173 N 19 0 19 0.003 0.854 View mutations
174 L 19 0 19 0.004 0.867 View mutations
175 G 19 0 19 0.001 0.852 View mutations