P25445 (P25445)

Overview
Predicted structure (AF):
AF-P25445-F1-model_v4
Uniprot entry:
P25445
Gene:
P25445
Protein length:
335 residues
Mutations found:
6364
Benign based on D2Deep prediction:
4666 out of 6364 mutations
Pathogenic based on D2Deep prediction:
1698 out of 6364 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 6364 mutations across 335 unique positions. There are 4666 benign and 1698 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 W 19 0 19 0.004 0.841 View mutations
177 L 18 1 19 0.127 0.877 View mutations
178 C 19 0 19 0.006 0.908 View mutations
179 L 19 0 19 0.008 0.851 View mutations
180 L 19 0 19 0.006 0.818 View mutations
181 L 19 0 19 0.001 0.840 View mutations
182 L 19 0 19 0.002 0.789 View mutations
183 P 19 0 19 0.003 0.828 View mutations
184 I 19 0 19 0.006 0.838 View mutations
185 P 19 0 19 0.000 0.833 View mutations
186 L 19 0 19 0.018 0.917 View mutations
187 I 16 3 19 0.198 0.732 View mutations
188 V 19 0 19 0.016 0.842 View mutations
189 W 17 2 19 0.108 0.799 View mutations
190 V 19 0 19 0.019 0.882 View mutations
191 K 19 0 19 0.005 0.916 View mutations
192 R 19 0 19 0.000 0.926 View mutations
193 K 19 0 19 0.000 0.913 View mutations
194 E 19 0 19 0.000 0.967 View mutations
195 V 19 0 19 0.004 0.975 View mutations
196 Q 19 0 19 0.000 0.958 View mutations
197 K 19 0 19 0.010 0.968 View mutations
198 T 19 0 19 0.001 1.000 View mutations
199 C 19 0 19 0.001 0.981 View mutations
200 R 19 0 19 0.001 0.959 View mutations