P25445 (P25445)

Overview
Predicted structure (AF):
AF-P25445-F1-model_v4
Uniprot entry:
P25445
Gene:
P25445
Protein length:
335 residues
Mutations found:
6364
Benign based on D2Deep prediction:
4666 out of 6364 mutations
Pathogenic based on D2Deep prediction:
1698 out of 6364 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 6364 mutations across 335 unique positions. There are 4666 benign and 1698 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 K 19 0 19 0.001 0.949 View mutations
202 H 19 0 19 0.001 0.946 View mutations
203 R 19 0 19 0.000 0.932 View mutations
204 K 19 0 19 0.000 0.925 View mutations
205 E 19 0 19 0.001 0.916 View mutations
206 N 19 0 19 0.041 0.939 View mutations
207 Q 19 0 19 0.026 0.957 View mutations
208 G 19 0 19 0.001 0.878 View mutations
209 S 19 0 19 0.001 0.983 View mutations
210 H 19 0 19 0.008 0.939 View mutations
211 E 19 0 19 0.069 0.924 View mutations
212 S 12 7 19 0.462 0.604 View mutations
213 P 19 0 19 0.034 0.861 View mutations
214 T 19 0 19 0.017 0.856 View mutations
215 L 14 5 19 0.305 0.674 View mutations
216 N 19 0 19 0.108 0.910 View mutations
217 P 18 1 19 0.039 0.794 View mutations
218 E 15 4 19 0.249 0.666 View mutations
219 T 19 0 19 0.035 0.877 View mutations
220 V 19 0 19 0.003 0.814 View mutations
221 A 19 0 19 0.004 0.732 View mutations
222 I 19 0 19 0.069 0.759 View mutations
223 N 19 0 19 0.000 0.724 View mutations
224 L 9 10 19 0.419 0.449 View mutations
225 S 19 0 19 0.023 0.539 View mutations