P31749 (AKT1)

Overview
Predicted structure (AF):
AF-P31749-F1-model_v4
Uniprot entry:
P31749
Gene:
AKT1
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
5131 out of 9119 mutations
Pathogenic based on D2Deep prediction:
3988 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9119 mutations across 480 unique positions. There are 5131 benign and 3988 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 V 0 19 19 0.963 0.608 View mutations
227 M 18 1 19 0.055 0.489 View mutations
228 E 2 17 19 0.877 0.569 View mutations
229 Y 0 19 19 0.988 0.640 View mutations
230 A 1 18 19 0.943 0.535 View mutations
231 N 0 19 19 0.947 0.534 View mutations
232 G 0 19 19 1.000 0.723 View mutations
233 G 0 19 19 1.000 0.642 View mutations
234 E 0 19 19 1.000 0.620 View mutations
235 L 7 12 19 0.574 0.548 View mutations
236 F 8 11 19 0.595 0.521 View mutations
237 F 5 14 19 0.734 0.536 View mutations
238 H 0 19 19 1.000 0.637 View mutations
239 L 0 19 19 0.999 0.687 View mutations
240 S 17 2 19 0.181 0.441 View mutations
241 R 10 9 19 0.484 0.498 View mutations
242 E 2 17 19 0.888 0.586 View mutations
243 R 2 17 19 0.859 0.544 View mutations
244 V 19 0 19 0.011 0.431 View mutations
245 F 0 19 19 0.992 0.730 View mutations
246 S 8 11 19 0.587 0.522 View mutations
247 E 19 0 19 0.002 0.342 View mutations
248 D 5 14 19 0.682 0.528 View mutations
249 R 0 19 19 0.989 0.711 View mutations
250 A 1 18 19 0.927 0.647 View mutations