P31749 (AKT1)

Overview
Predicted structure (AF):
AF-P31749-F1-model_v4
Uniprot entry:
P31749
Gene:
AKT1
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
5131 out of 9119 mutations
Pathogenic based on D2Deep prediction:
3988 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9119 mutations across 480 unique positions. There are 5131 benign and 3988 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 V 1 18 19 0.904 0.513 View mutations
202 L 19 0 19 0.028 0.433 View mutations
203 Q 19 0 19 0.000 0.549 View mutations
204 N 19 0 19 0.000 0.581 View mutations
205 S 19 0 19 0.029 0.557 View mutations
206 R 6 13 19 0.604 0.407 View mutations
207 H 0 19 19 0.970 0.452 View mutations
208 P 10 9 19 0.464 0.423 View mutations
209 F 17 2 19 0.122 0.543 View mutations
210 L 19 0 19 0.001 0.493 View mutations
211 T 19 0 19 0.050 0.630 View mutations
212 A 10 9 19 0.460 0.465 View mutations
213 L 1 18 19 0.887 0.401 View mutations
214 K 2 17 19 0.871 0.402 View mutations
215 Y 15 4 19 0.222 0.435 View mutations
216 S 2 17 19 0.901 0.480 View mutations
217 F 7 12 19 0.635 0.528 View mutations
218 Q 13 6 19 0.431 0.498 View mutations
219 T 19 0 19 0.021 0.491 View mutations
220 H 19 0 19 0.000 0.588 View mutations
221 D 19 0 19 0.001 0.365 View mutations
222 R 13 6 19 0.282 0.493 View mutations
223 L 19 0 19 0.001 0.419 View mutations
224 C 8 11 19 0.595 0.501 View mutations
225 F 4 15 19 0.776 0.562 View mutations