P31749 (AKT1)

Overview
Predicted structure (AF):
AF-P31749-F1-model_v4
Uniprot entry:
P31749
Gene:
AKT1
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
5131 out of 9119 mutations
Pathogenic based on D2Deep prediction:
3988 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9119 mutations across 480 unique positions. There are 5131 benign and 3988 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 K 0 19 19 1.000 0.936 View mutations
277 L 0 19 19 0.999 0.782 View mutations
278 E 0 19 19 0.998 0.841 View mutations
279 N 0 19 19 1.000 0.911 View mutations
280 L 0 19 19 0.984 0.817 View mutations
281 M 1 18 19 0.948 0.760 View mutations
282 L 0 19 19 1.000 0.880 View mutations
283 D 0 19 19 1.000 0.788 View mutations
284 K 0 19 19 0.998 0.577 View mutations
285 D 1 18 19 0.948 0.696 View mutations
286 G 4 15 19 0.779 0.773 View mutations
287 H 1 18 19 0.913 0.791 View mutations
288 I 2 17 19 0.916 0.678 View mutations
289 K 6 13 19 0.713 0.612 View mutations
290 I 0 19 19 1.000 0.817 View mutations
291 T 1 18 19 0.948 0.822 View mutations
292 D 0 19 19 1.000 0.904 View mutations
293 F 14 5 19 0.353 0.290 View mutations
294 G 0 19 19 1.000 0.854 View mutations
295 L 7 12 19 0.606 0.554 View mutations
296 C 19 0 19 0.038 0.313 View mutations
297 K 1 18 19 0.924 0.660 View mutations
298 E 6 13 19 0.708 0.525 View mutations
299 G 4 15 19 0.783 0.441 View mutations
300 I 10 9 19 0.539 0.423 View mutations