P31749 (AKT1)

Overview
Predicted structure (AF):
AF-P31749-F1-model_v4
Uniprot entry:
P31749
Gene:
AKT1
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
5131 out of 9119 mutations
Pathogenic based on D2Deep prediction:
3988 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9119 mutations across 480 unique positions. There are 5131 benign and 3988 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
326 Y 0 19 19 0.994 0.828 View mutations
327 G 1 18 19 0.957 0.742 View mutations
328 R 2 17 19 0.884 0.629 View mutations
329 A 4 15 19 0.749 0.642 View mutations
330 V 0 19 19 1.000 0.960 View mutations
331 D 0 19 19 1.000 0.916 View mutations
332 W 0 19 19 1.000 0.742 View mutations
333 W 0 19 19 1.000 0.879 View mutations
334 G 0 19 19 1.000 0.766 View mutations
335 L 10 9 19 0.460 0.492 View mutations
336 G 13 6 19 0.305 0.355 View mutations
337 V 6 13 19 0.705 0.655 View mutations
338 V 11 8 19 0.383 0.460 View mutations
339 M 18 1 19 0.063 0.401 View mutations
340 Y 0 19 19 1.000 0.819 View mutations
341 E 19 0 19 0.002 0.099 View mutations
342 M 10 9 19 0.418 0.484 View mutations
343 M 4 15 19 0.784 0.597 View mutations
344 C 0 19 19 0.967 0.707 View mutations
345 G 10 9 19 0.505 0.474 View mutations
346 R 5 14 19 0.702 0.605 View mutations
347 L 0 19 19 1.000 0.778 View mutations
348 P 0 19 19 1.000 0.874 View mutations
349 F 0 19 19 1.000 0.708 View mutations
350 Y 1 18 19 0.910 0.660 View mutations