P31749 (AKT1)

Overview
Predicted structure (AF):
AF-P31749-F1-model_v4
Uniprot entry:
P31749
Gene:
AKT1
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
5131 out of 9119 mutations
Pathogenic based on D2Deep prediction:
3988 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9119 mutations across 480 unique positions. There are 5131 benign and 3988 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 K 19 0 19 0.044 0.619 View mutations
302 D 18 1 19 0.071 0.464 View mutations
303 G 5 14 19 0.734 0.454 View mutations
304 A 2 17 19 0.879 0.419 View mutations
305 T 19 0 19 0.003 0.383 View mutations
306 M 2 17 19 0.886 0.542 View mutations
307 K 16 3 19 0.177 0.474 View mutations
308 T 18 1 19 0.115 0.229 View mutations
309 F 19 0 19 0.010 0.199 View mutations
310 C 14 5 19 0.264 0.297 View mutations
311 G 3 16 19 0.787 0.812 View mutations
312 T 5 14 19 0.683 0.730 View mutations
313 P 10 9 19 0.451 0.478 View mutations
314 E 0 19 19 1.000 0.905 View mutations
315 Y 0 19 19 0.998 0.938 View mutations
316 L 7 12 19 0.635 0.603 View mutations
317 A 2 17 19 0.897 0.800 View mutations
318 P 6 13 19 0.652 0.623 View mutations
319 E 0 19 19 0.960 0.759 View mutations
320 V 8 11 19 0.565 0.537 View mutations
321 L 4 15 19 0.782 0.659 View mutations
322 E 3 16 19 0.775 0.606 View mutations
323 D 16 3 19 0.181 0.338 View mutations
324 N 2 17 19 0.917 0.587 View mutations
325 D 1 18 19 0.882 0.653 View mutations