P31749 (AKT1)

Overview
Predicted structure (AF):
AF-P31749-F1-model_v4
Uniprot entry:
P31749
Gene:
AKT1
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
5131 out of 9119 mutations
Pathogenic based on D2Deep prediction:
3988 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9119 mutations across 480 unique positions. There are 5131 benign and 3988 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
351 N 3 16 19 0.815 0.539 View mutations
352 Q 17 2 19 0.114 0.489 View mutations
353 D 1 18 19 0.948 0.588 View mutations
354 H 1 18 19 0.957 0.628 View mutations
355 E 1 18 19 0.942 0.581 View mutations
356 K 18 1 19 0.074 0.487 View mutations
357 L 1 18 19 0.942 0.677 View mutations
358 F 0 19 19 1.000 0.694 View mutations
359 E 3 16 19 0.865 0.584 View mutations
360 L 19 0 19 0.013 0.449 View mutations
361 I 4 15 19 0.795 0.601 View mutations
362 L 3 16 19 0.836 0.593 View mutations
363 M 6 13 19 0.677 0.438 View mutations
364 E 4 15 19 0.805 0.465 View mutations
365 E 19 0 19 0.005 0.449 View mutations
366 I 2 17 19 0.869 0.593 View mutations
367 R 12 7 19 0.304 0.481 View mutations
368 F 0 19 19 1.000 0.628 View mutations
369 P 17 2 19 0.115 0.332 View mutations
370 R 19 0 19 0.003 0.400 View mutations
371 T 19 0 19 0.009 0.420 View mutations
372 L 15 4 19 0.289 0.451 View mutations
373 G 6 13 19 0.657 0.429 View mutations
374 P 19 0 19 0.053 0.561 View mutations
375 E 19 0 19 0.001 0.480 View mutations