P31749 (AKT1)

Overview
Predicted structure (AF):
AF-P31749-F1-model_v4
Uniprot entry:
P31749
Gene:
AKT1
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
5131 out of 9119 mutations
Pathogenic based on D2Deep prediction:
3988 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9119 mutations across 480 unique positions. There are 5131 benign and 3988 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 S 19 0 19 0.002 0.916 View mutations
127 D 19 0 19 0.016 0.891 View mutations
128 N 19 0 19 0.016 0.943 View mutations
129 S 19 0 19 0.003 1.000 View mutations
130 G 18 1 19 0.076 0.925 View mutations
131 A 18 1 19 0.085 0.896 View mutations
132 E 19 0 19 0.021 0.939 View mutations
133 E 19 0 19 0.003 0.918 View mutations
134 M 19 0 19 0.001 0.914 View mutations
135 E 19 0 19 0.001 0.931 View mutations
136 V 19 0 19 0.012 0.872 View mutations
137 S 19 0 19 0.005 0.919 View mutations
138 L 19 0 19 0.008 0.893 View mutations
139 A 19 0 19 0.003 0.889 View mutations
140 K 19 0 19 0.009 0.845 View mutations
141 P 19 0 19 0.027 0.806 View mutations
142 K 19 0 19 0.002 0.828 View mutations
143 H 19 0 19 0.001 0.784 View mutations
144 R 19 0 19 0.010 0.642 View mutations
145 V 19 0 19 0.001 0.748 View mutations
146 T 19 0 19 0.000 0.658 View mutations
147 M 9 10 19 0.503 0.440 View mutations
148 N 19 0 19 0.000 0.623 View mutations
149 E 19 0 19 0.028 0.617 View mutations
150 F 19 0 19 0.001 0.382 View mutations