P31749 (AKT1)

Overview
Predicted structure (AF):
AF-P31749-F1-model_v4
Uniprot entry:
P31749
Gene:
AKT1
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
5131 out of 9119 mutations
Pathogenic based on D2Deep prediction:
3988 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9119 mutations across 480 unique positions. There are 5131 benign and 3988 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 E 18 1 19 0.144 0.467 View mutations
152 Y 7 12 19 0.660 0.430 View mutations
153 L 17 2 19 0.139 0.424 View mutations
154 K 9 10 19 0.557 0.504 View mutations
155 L 1 18 19 0.946 0.549 View mutations
156 L 3 16 19 0.766 0.595 View mutations
157 G 2 17 19 0.912 0.718 View mutations
158 K 0 19 19 0.997 0.663 View mutations
159 G 0 19 19 0.988 0.866 View mutations
160 T 0 19 19 0.978 0.775 View mutations
161 F 0 19 19 1.000 0.762 View mutations
162 G 0 19 19 1.000 0.848 View mutations
163 K 0 19 19 1.000 0.679 View mutations
164 V 0 19 19 1.000 0.743 View mutations
165 I 3 16 19 0.846 0.573 View mutations
166 L 0 19 19 1.000 0.558 View mutations
167 V 10 9 19 0.452 0.422 View mutations
168 K 3 16 19 0.809 0.505 View mutations
169 E 15 4 19 0.256 0.404 View mutations
170 K 18 1 19 0.073 0.384 View mutations
171 A 12 7 19 0.401 0.436 View mutations
172 T 19 0 19 0.000 0.494 View mutations
173 G 19 0 19 0.000 0.534 View mutations
174 R 19 0 19 0.001 0.564 View mutations
175 Y 10 9 19 0.436 0.425 View mutations