P31751 (AKT2)

Overview
Predicted structure (AF):
AF-P31751-F1-model_v4
Uniprot entry:
P31751
Gene:
AKT2
Protein length:
481 residues
Mutations found:
9138
Benign based on D2Deep prediction:
5179 out of 9138 mutations
Pathogenic based on D2Deep prediction:
3959 out of 9138 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9138 mutations across 481 unique positions. There are 5179 benign and 3959 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 C 10 9 19 0.460 0.498 View mutations
227 F 19 0 19 0.049 0.375 View mutations
228 V 0 19 19 0.989 0.659 View mutations
229 M 0 19 19 1.000 0.522 View mutations
230 E 1 18 19 0.949 0.598 View mutations
231 Y 1 18 19 0.939 0.647 View mutations
232 A 1 18 19 0.944 0.565 View mutations
233 N 0 19 19 1.000 0.576 View mutations
234 G 0 19 19 1.000 0.763 View mutations
235 G 8 11 19 0.500 0.530 View mutations
236 E 17 2 19 0.176 0.386 View mutations
237 L 1 18 19 0.942 0.720 View mutations
238 F 0 19 19 1.000 0.646 View mutations
239 F 0 19 19 0.993 0.592 View mutations
240 H 3 16 19 0.749 0.609 View mutations
241 L 8 11 19 0.630 0.534 View mutations
242 S 2 17 19 0.884 0.564 View mutations
243 R 2 17 19 0.860 0.559 View mutations
244 E 19 0 19 0.004 0.380 View mutations
245 R 12 7 19 0.398 0.482 View mutations
246 V 14 5 19 0.328 0.458 View mutations
247 F 19 0 19 0.019 0.275 View mutations
248 T 5 14 19 0.697 0.560 View mutations
249 E 0 19 19 1.000 0.661 View mutations
250 E 4 15 19 0.726 0.534 View mutations