P31751 (AKT2)

Overview
Predicted structure (AF):
AF-P31751-F1-model_v4
Uniprot entry:
P31751
Gene:
AKT2
Protein length:
481 residues
Mutations found:
9138
Benign based on D2Deep prediction:
5179 out of 9138 mutations
Pathogenic based on D2Deep prediction:
3959 out of 9138 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9138 mutations across 481 unique positions. There are 5179 benign and 3959 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 I 1 18 19 0.948 0.821 View mutations
277 K 2 17 19 0.897 0.869 View mutations
278 L 0 19 19 0.994 0.840 View mutations
279 E 1 18 19 0.969 0.823 View mutations
280 N 0 19 19 1.000 0.916 View mutations
281 L 0 19 19 1.000 0.823 View mutations
282 M 1 18 19 0.947 0.770 View mutations
283 L 0 19 19 1.000 0.883 View mutations
284 D 0 19 19 1.000 0.786 View mutations
285 K 2 17 19 0.920 0.563 View mutations
286 D 4 15 19 0.812 0.626 View mutations
287 G 0 19 19 0.999 0.964 View mutations
288 H 0 19 19 1.000 0.825 View mutations
289 I 1 18 19 0.931 0.729 View mutations
290 K 0 19 19 1.000 0.806 View mutations
291 I 0 19 19 0.996 0.831 View mutations
292 T 1 18 19 0.947 0.821 View mutations
293 D 11 8 19 0.420 0.435 View mutations
294 F 0 19 19 1.000 0.952 View mutations
295 G 9 10 19 0.523 0.519 View mutations
296 L 11 8 19 0.404 0.468 View mutations
297 C 0 19 19 0.999 0.683 View mutations
298 K 3 16 19 0.860 0.644 View mutations
299 E 0 19 19 0.995 0.563 View mutations
300 G 4 15 19 0.809 0.457 View mutations