P31751 (AKT2)

Overview
Predicted structure (AF):
AF-P31751-F1-model_v4
Uniprot entry:
P31751
Gene:
AKT2
Protein length:
481 residues
Mutations found:
9138
Benign based on D2Deep prediction:
5179 out of 9138 mutations
Pathogenic based on D2Deep prediction:
3959 out of 9138 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9138 mutations across 481 unique positions. There are 5179 benign and 3959 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 R 19 0 19 0.013 0.537 View mutations
177 Y 13 6 19 0.345 0.498 View mutations
178 Y 6 13 19 0.654 0.523 View mutations
179 A 0 19 19 1.000 0.828 View mutations
180 M 1 18 19 0.904 0.592 View mutations
181 K 0 19 19 0.999 0.767 View mutations
182 I 1 18 19 0.944 0.705 View mutations
183 L 0 19 19 1.000 0.694 View mutations
184 R 1 18 19 0.939 0.587 View mutations
185 K 12 7 19 0.348 0.451 View mutations
186 E 16 3 19 0.129 0.440 View mutations
187 V 5 14 19 0.729 0.553 View mutations
188 I 2 17 19 0.871 0.570 View mutations
189 I 4 15 19 0.765 0.566 View mutations
190 A 17 2 19 0.193 0.498 View mutations
191 K 2 17 19 0.801 0.510 View mutations
192 D 11 8 19 0.518 0.427 View mutations
193 E 2 17 19 0.879 0.452 View mutations
194 V 3 16 19 0.787 0.454 View mutations
195 A 18 1 19 0.041 0.442 View mutations
196 H 16 3 19 0.123 0.483 View mutations
197 T 19 0 19 0.075 0.355 View mutations
198 V 12 7 19 0.396 0.414 View mutations
199 T 19 0 19 0.030 0.479 View mutations
200 E 0 19 19 1.000 0.571 View mutations