P31751 (AKT2)

Overview
Predicted structure (AF):
AF-P31751-F1-model_v4
Uniprot entry:
P31751
Gene:
AKT2
Protein length:
481 residues
Mutations found:
9138
Benign based on D2Deep prediction:
5179 out of 9138 mutations
Pathogenic based on D2Deep prediction:
3959 out of 9138 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9138 mutations across 481 unique positions. There are 5179 benign and 3959 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 S 6 13 19 0.708 0.430 View mutations
202 R 18 1 19 0.081 0.377 View mutations
203 V 19 0 19 0.000 0.461 View mutations
204 L 19 0 19 0.003 0.400 View mutations
205 Q 19 0 19 0.061 0.503 View mutations
206 N 12 7 19 0.364 0.464 View mutations
207 T 15 4 19 0.202 0.458 View mutations
208 R 19 0 19 0.052 0.504 View mutations
209 H 19 0 19 0.075 0.359 View mutations
210 P 19 0 19 0.000 0.474 View mutations
211 F 10 9 19 0.556 0.447 View mutations
212 L 0 19 19 0.998 0.417 View mutations
213 T 6 13 19 0.719 0.407 View mutations
214 A 12 7 19 0.386 0.488 View mutations
215 L 13 6 19 0.346 0.432 View mutations
216 K 4 15 19 0.680 0.423 View mutations
217 Y 9 10 19 0.492 0.434 View mutations
218 A 9 10 19 0.522 0.501 View mutations
219 F 18 1 19 0.094 0.388 View mutations
220 Q 19 0 19 0.000 0.455 View mutations
221 T 19 0 19 0.013 0.452 View mutations
222 H 19 0 19 0.009 0.557 View mutations
223 D 19 0 19 0.000 0.478 View mutations
224 R 12 7 19 0.418 0.484 View mutations
225 L 4 15 19 0.726 0.563 View mutations