P31751 (AKT2)

Overview
Predicted structure (AF):
AF-P31751-F1-model_v4
Uniprot entry:
P31751
Gene:
AKT2
Protein length:
481 residues
Mutations found:
9138
Benign based on D2Deep prediction:
5179 out of 9138 mutations
Pathogenic based on D2Deep prediction:
3959 out of 9138 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9138 mutations across 481 unique positions. There are 5179 benign and 3959 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 I 7 12 19 0.596 0.501 View mutations
302 S 17 2 19 0.103 0.562 View mutations
303 D 3 16 19 0.778 0.434 View mutations
304 G 3 16 19 0.847 0.513 View mutations
305 A 17 2 19 0.130 0.436 View mutations
306 T 11 8 19 0.415 0.415 View mutations
307 M 11 8 19 0.456 0.491 View mutations
308 K 19 0 19 0.013 0.442 View mutations
309 T 19 0 19 0.008 0.200 View mutations
310 F 5 14 19 0.666 0.653 View mutations
311 C 2 17 19 0.866 0.850 View mutations
312 G 19 0 19 0.001 0.036 View mutations
313 T 19 0 19 0.005 0.005 View mutations
314 P 0 19 19 1.000 0.924 View mutations
315 E 0 19 19 1.000 0.905 View mutations
316 Y 2 17 19 0.918 0.830 View mutations
317 L 1 18 19 0.956 0.856 View mutations
318 A 9 10 19 0.565 0.519 View mutations
319 P 0 19 19 1.000 0.843 View mutations
320 E 5 14 19 0.735 0.628 View mutations
321 V 7 12 19 0.679 0.564 View mutations
322 L 0 19 19 0.983 0.787 View mutations
323 E 14 5 19 0.235 0.421 View mutations
324 D 0 19 19 0.999 0.726 View mutations
325 N 1 18 19 0.916 0.615 View mutations