P31751 (AKT2)

Overview
Predicted structure (AF):
AF-P31751-F1-model_v4
Uniprot entry:
P31751
Gene:
AKT2
Protein length:
481 residues
Mutations found:
9138
Benign based on D2Deep prediction:
5179 out of 9138 mutations
Pathogenic based on D2Deep prediction:
3959 out of 9138 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9138 mutations across 481 unique positions. There are 5179 benign and 3959 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
326 D 1 18 19 0.938 0.661 View mutations
327 Y 0 19 19 1.000 0.829 View mutations
328 G 0 19 19 0.997 0.783 View mutations
329 R 3 16 19 0.813 0.611 View mutations
330 A 1 18 19 0.952 0.716 View mutations
331 V 0 19 19 1.000 0.936 View mutations
332 D 0 19 19 1.000 0.910 View mutations
333 W 0 19 19 0.994 0.717 View mutations
334 W 0 19 19 1.000 0.855 View mutations
335 G 0 19 19 1.000 0.759 View mutations
336 L 17 2 19 0.146 0.375 View mutations
337 G 10 9 19 0.448 0.480 View mutations
338 V 4 15 19 0.760 0.736 View mutations
339 V 16 3 19 0.184 0.341 View mutations
340 M 8 11 19 0.577 0.515 View mutations
341 Y 19 0 19 0.000 0.193 View mutations
342 E 5 14 19 0.686 0.676 View mutations
343 M 0 19 19 1.000 0.785 View mutations
344 M 2 17 19 0.917 0.626 View mutations
345 C 17 2 19 0.114 0.347 View mutations
346 G 7 12 19 0.573 0.629 View mutations
347 R 1 18 19 0.972 0.694 View mutations
348 L 0 19 19 0.999 0.760 View mutations
349 P 0 19 19 1.000 0.853 View mutations
350 F 0 19 19 0.962 0.696 View mutations