P31751 (AKT2)

Overview
Predicted structure (AF):
AF-P31751-F1-model_v4
Uniprot entry:
P31751
Gene:
AKT2
Protein length:
481 residues
Mutations found:
9138
Benign based on D2Deep prediction:
5179 out of 9138 mutations
Pathogenic based on D2Deep prediction:
3959 out of 9138 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9138 mutations across 481 unique positions. There are 5179 benign and 3959 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
351 Y 1 18 19 0.911 0.642 View mutations
352 N 5 14 19 0.727 0.524 View mutations
353 Q 8 11 19 0.674 0.437 View mutations
354 D 1 18 19 0.946 0.596 View mutations
355 H 1 18 19 0.945 0.618 View mutations
356 E 10 9 19 0.441 0.495 View mutations
357 R 16 3 19 0.180 0.488 View mutations
358 L 0 19 19 1.000 0.681 View mutations
359 F 0 19 19 1.000 0.691 View mutations
360 E 19 0 19 0.015 0.382 View mutations
361 L 10 9 19 0.446 0.497 View mutations
362 I 0 19 19 0.990 0.664 View mutations
363 L 1 18 19 0.956 0.601 View mutations
364 M 14 5 19 0.287 0.429 View mutations
365 E 18 1 19 0.116 0.490 View mutations
366 E 5 14 19 0.675 0.534 View mutations
367 I 14 5 19 0.348 0.448 View mutations
368 R 1 18 19 0.947 0.559 View mutations
369 F 12 7 19 0.390 0.469 View mutations
370 P 19 0 19 0.012 0.277 View mutations
371 R 18 1 19 0.105 0.379 View mutations
372 T 19 0 19 0.000 0.366 View mutations
373 L 14 5 19 0.324 0.463 View mutations
374 S 11 8 19 0.454 0.433 View mutations
375 P 17 2 19 0.128 0.506 View mutations