P31751 (AKT2)

Overview
Predicted structure (AF):
AF-P31751-F1-model_v4
Uniprot entry:
P31751
Gene:
AKT2
Protein length:
481 residues
Mutations found:
9138
Benign based on D2Deep prediction:
5179 out of 9138 mutations
Pathogenic based on D2Deep prediction:
3959 out of 9138 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9138 mutations across 481 unique positions. There are 5179 benign and 3959 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 S 19 0 19 0.001 0.909 View mutations
127 P 19 0 19 0.024 0.906 View mutations
128 S 19 0 19 0.007 0.953 View mutations
129 D 19 0 19 0.005 0.919 View mutations
130 S 19 0 19 0.001 0.935 View mutations
131 S 18 1 19 0.040 0.947 View mutations
132 T 19 0 19 0.003 0.920 View mutations
133 T 19 0 19 0.003 0.917 View mutations
134 E 19 0 19 0.000 0.924 View mutations
135 E 19 0 19 0.000 0.916 View mutations
136 M 19 0 19 0.001 0.892 View mutations
137 E 19 0 19 0.005 0.883 View mutations
138 V 19 0 19 0.001 0.863 View mutations
139 A 19 0 19 0.001 0.866 View mutations
140 V 19 0 19 0.015 0.856 View mutations
141 S 19 0 19 0.003 0.896 View mutations
142 K 19 0 19 0.001 0.858 View mutations
143 A 19 0 19 0.000 0.807 View mutations
144 R 19 0 19 0.003 0.791 View mutations
145 A 19 0 19 0.000 0.770 View mutations
146 K 19 0 19 0.000 0.591 View mutations
147 V 16 3 19 0.175 0.637 View mutations
148 T 19 0 19 0.000 0.643 View mutations
149 M 19 0 19 0.008 0.476 View mutations
150 N 19 0 19 0.000 0.602 View mutations