P31751 (AKT2)

Overview
Predicted structure (AF):
AF-P31751-F1-model_v4
Uniprot entry:
P31751
Gene:
AKT2
Protein length:
481 residues
Mutations found:
9138
Benign based on D2Deep prediction:
5179 out of 9138 mutations
Pathogenic based on D2Deep prediction:
3959 out of 9138 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9138 mutations across 481 unique positions. There are 5179 benign and 3959 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 D 13 6 19 0.377 0.495 View mutations
152 F 1 18 19 0.937 0.490 View mutations
153 D 19 0 19 0.058 0.428 View mutations
154 Y 11 8 19 0.454 0.437 View mutations
155 L 0 19 19 0.971 0.478 View mutations
156 K 1 18 19 0.944 0.578 View mutations
157 L 5 14 19 0.723 0.540 View mutations
158 L 0 19 19 0.997 0.677 View mutations
159 G 0 19 19 0.981 0.805 View mutations
160 K 0 19 19 0.975 0.691 View mutations
161 G 0 19 19 1.000 0.890 View mutations
162 T 0 19 19 1.000 0.804 View mutations
163 F 0 19 19 1.000 0.793 View mutations
164 G 0 19 19 1.000 0.877 View mutations
165 K 1 18 19 0.957 0.687 View mutations
166 V 0 19 19 1.000 0.768 View mutations
167 I 2 17 19 0.875 0.609 View mutations
168 L 0 19 19 0.996 0.583 View mutations
169 V 10 9 19 0.452 0.499 View mutations
170 R 9 10 19 0.584 0.502 View mutations
171 E 1 18 19 0.945 0.485 View mutations
172 K 9 10 19 0.476 0.500 View mutations
173 A 18 1 19 0.030 0.405 View mutations
174 T 19 0 19 0.003 0.454 View mutations
175 G 19 0 19 0.024 0.485 View mutations