P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 E 8 11 19 0.628 0.524 View mutations
227 G 8 11 19 0.570 0.540 View mutations
228 L 2 17 19 0.879 0.689 View mutations
229 L 0 19 19 1.000 0.679 View mutations
230 A 3 16 19 0.858 0.593 View mutations
231 I 4 15 19 0.798 0.666 View mutations
232 F 1 18 19 0.965 0.753 View mutations
233 K 0 19 19 1.000 0.756 View mutations
234 S 1 18 19 0.948 0.681 View mutations
235 G 17 2 19 0.133 0.262 View mutations
236 G 18 1 19 0.033 0.178 View mutations
237 I 1 18 19 0.926 0.816 View mutations
238 P 0 19 19 0.996 0.767 View mutations
239 A 2 17 19 0.874 0.631 View mutations
240 L 2 17 19 0.777 0.705 View mutations
241 V 10 9 19 0.489 0.487 View mutations
242 K 2 17 19 0.866 0.565 View mutations
243 M 3 16 19 0.809 0.618 View mutations
244 L 9 10 19 0.531 0.509 View mutations
245 G 5 14 19 0.674 0.578 View mutations
246 S 19 0 19 0.020 0.345 View mutations
247 P 18 1 19 0.059 0.359 View mutations
248 V 5 14 19 0.707 0.546 View mutations
249 D 1 18 19 0.948 0.681 View mutations
250 S 3 16 19 0.875 0.631 View mutations