P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 H 10 9 19 0.464 0.497 View mutations
177 Q 6 13 19 0.595 0.543 View mutations
178 L 10 9 19 0.508 0.488 View mutations
179 S 12 7 19 0.390 0.444 View mutations
180 K 3 16 19 0.788 0.628 View mutations
181 K 15 4 19 0.246 0.381 View mutations
182 E 9 10 19 0.487 0.512 View mutations
183 A 3 16 19 0.806 0.660 View mutations
184 S 4 15 19 0.784 0.599 View mutations
185 R 19 0 19 0.013 0.304 View mutations
186 H 19 0 19 0.001 0.399 View mutations
187 A 8 11 19 0.556 0.532 View mutations
188 I 9 10 19 0.517 0.507 View mutations
189 M 4 15 19 0.721 0.573 View mutations
190 R 13 6 19 0.290 0.483 View mutations
191 S 1 18 19 0.871 0.605 View mutations
192 P 19 0 19 0.087 0.429 View mutations
193 Q 19 0 19 0.030 0.476 View mutations
194 M 6 13 19 0.682 0.535 View mutations
195 V 16 3 19 0.221 0.376 View mutations
196 S 19 0 19 0.002 0.433 View mutations
197 A 19 0 19 0.041 0.391 View mutations
198 I 3 16 19 0.815 0.534 View mutations
199 V 18 1 19 0.068 0.390 View mutations
200 R 14 5 19 0.250 0.486 View mutations