P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 A 0 19 19 0.994 0.873 View mutations
277 G 7 12 19 0.622 0.591 View mutations
278 G 3 16 19 0.804 0.782 View mutations
279 L 4 15 19 0.833 0.687 View mutations
280 Q 10 9 19 0.461 0.489 View mutations
281 K 0 19 19 1.000 0.713 View mutations
282 M 2 17 19 0.934 0.710 View mutations
283 V 1 18 19 0.957 0.709 View mutations
284 A 2 17 19 0.846 0.590 View mutations
285 L 0 19 19 0.997 0.768 View mutations
286 L 11 8 19 0.457 0.477 View mutations
287 N 19 0 19 0.049 0.432 View mutations
288 K 6 13 19 0.692 0.560 View mutations
289 T 18 1 19 0.047 0.369 View mutations
290 N 0 19 19 0.995 0.682 View mutations
291 V 7 12 19 0.555 0.553 View mutations
292 K 4 15 19 0.757 0.705 View mutations
293 F 17 2 19 0.146 0.262 View mutations
294 L 2 17 19 0.895 0.757 View mutations
295 A 13 6 19 0.338 0.373 View mutations
296 I 15 4 19 0.189 0.309 View mutations
297 T 3 16 19 0.819 0.654 View mutations
298 T 0 19 19 0.996 0.848 View mutations
299 D 0 19 19 1.000 0.832 View mutations
300 C 0 19 19 1.000 0.837 View mutations