P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 T 4 15 19 0.744 0.553 View mutations
202 M 18 1 19 0.088 0.476 View mutations
203 Q 19 0 19 0.001 0.436 View mutations
204 N 19 0 19 0.024 0.497 View mutations
205 T 14 5 19 0.269 0.467 View mutations
206 N 6 13 19 0.652 0.503 View mutations
207 D 4 15 19 0.775 0.546 View mutations
208 V 19 0 19 0.047 0.376 View mutations
209 E 4 15 19 0.689 0.529 View mutations
210 T 19 0 19 0.038 0.431 View mutations
211 A 13 6 19 0.288 0.452 View mutations
212 R 0 19 19 0.982 0.514 View mutations
213 C 2 17 19 0.781 0.392 View mutations
214 T 7 12 19 0.606 0.430 View mutations
215 A 18 1 19 0.115 0.379 View mutations
216 G 1 18 19 0.943 0.556 View mutations
217 T 9 10 19 0.530 0.500 View mutations
218 L 15 4 19 0.260 0.466 View mutations
219 H 12 7 19 0.447 0.471 View mutations
220 N 19 0 19 0.015 0.382 View mutations
221 L 19 0 19 0.066 0.384 View mutations
222 S 3 16 19 0.849 0.650 View mutations
223 H 19 0 19 0.001 0.360 View mutations
224 H 9 10 19 0.517 0.506 View mutations
225 R 5 14 19 0.719 0.558 View mutations