P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 L 0 19 19 0.962 0.776 View mutations
302 Q 16 3 19 0.148 0.305 View mutations
303 I 2 17 19 0.896 0.730 View mutations
304 L 0 19 19 1.000 0.887 View mutations
305 A 16 3 19 0.182 0.231 View mutations
306 Y 2 17 19 0.893 0.802 View mutations
307 G 2 17 19 0.833 0.860 View mutations
308 N 14 5 19 0.250 0.299 View mutations
309 Q 19 0 19 0.000 0.113 View mutations
310 E 3 16 19 0.773 0.789 View mutations
311 S 6 13 19 0.705 0.612 View mutations
312 K 19 0 19 0.000 0.068 View mutations
313 L 19 0 19 0.007 0.195 View mutations
314 I 1 18 19 0.951 0.793 View mutations
315 I 1 18 19 0.935 0.802 View mutations
316 L 17 2 19 0.201 0.197 View mutations
317 A 11 8 19 0.382 0.454 View mutations
318 S 11 8 19 0.385 0.462 View mutations
319 G 8 11 19 0.568 0.520 View mutations
320 G 0 19 19 0.993 0.741 View mutations
321 P 0 19 19 1.000 0.688 View mutations
322 Q 16 3 19 0.158 0.497 View mutations
323 A 18 1 19 0.053 0.442 View mutations
324 L 0 19 19 1.000 0.743 View mutations
325 V 0 19 19 1.000 0.714 View mutations