P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
326 N 14 5 19 0.306 0.491 View mutations
327 I 1 18 19 0.915 0.697 View mutations
328 M 1 18 19 0.923 0.696 View mutations
329 R 3 16 19 0.823 0.581 View mutations
330 T 9 10 19 0.546 0.506 View mutations
331 Y 1 18 19 0.945 0.648 View mutations
332 T 6 13 19 0.694 0.546 View mutations
333 Y 2 17 19 0.897 0.801 View mutations
334 E 0 19 19 1.000 0.862 View mutations
335 K 12 7 19 0.403 0.393 View mutations
336 L 8 11 19 0.563 0.557 View mutations
337 L 14 5 19 0.309 0.329 View mutations
338 W 10 9 19 0.461 0.480 View mutations
339 T 19 0 19 0.051 0.137 View mutations
340 T 1 18 19 0.948 0.812 View mutations
341 S 18 1 19 0.051 0.158 View mutations
342 R 7 12 19 0.649 0.610 View mutations
343 V 0 19 19 1.000 0.869 View mutations
344 L 0 19 19 0.983 0.905 View mutations
345 K 1 18 19 0.939 0.868 View mutations
346 V 4 15 19 0.773 0.723 View mutations
347 L 0 19 19 1.000 0.924 View mutations
348 S 0 19 19 0.972 1.000 View mutations
349 V 0 19 19 0.994 0.908 View mutations
350 C 1 18 19 0.936 0.799 View mutations