P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
351 S 7 12 19 0.628 0.563 View mutations
352 S 4 15 19 0.721 0.639 View mutations
353 N 0 19 19 0.997 0.768 View mutations
354 K 0 19 19 1.000 0.869 View mutations
355 P 0 19 19 0.999 0.766 View mutations
356 A 17 2 19 0.117 0.302 View mutations
357 I 3 16 19 0.861 0.711 View mutations
358 V 0 19 19 1.000 0.810 View mutations
359 E 1 18 19 0.923 0.691 View mutations
360 A 19 0 19 0.016 0.316 View mutations
361 G 14 5 19 0.275 0.401 View mutations
362 G 3 16 19 0.763 0.703 View mutations
363 M 0 19 19 1.000 0.659 View mutations
364 Q 6 13 19 0.719 0.448 View mutations
365 A 18 1 19 0.122 0.447 View mutations
366 L 4 15 19 0.790 0.560 View mutations
367 G 9 10 19 0.594 0.503 View mutations
368 L 6 13 19 0.698 0.441 View mutations
369 H 18 1 19 0.029 0.448 View mutations
370 L 19 0 19 0.045 0.451 View mutations
371 T 13 6 19 0.303 0.428 View mutations
372 D 10 9 19 0.457 0.421 View mutations
373 P 9 10 19 0.581 0.501 View mutations
374 S 6 13 19 0.735 0.530 View mutations
375 Q 17 2 19 0.200 0.369 View mutations