P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
376 R 19 0 19 0.047 0.353 View mutations
377 L 17 2 19 0.107 0.393 View mutations
378 V 2 17 19 0.906 0.532 View mutations
379 Q 7 12 19 0.632 0.525 View mutations
380 N 3 16 19 0.873 0.662 View mutations
381 C 5 14 19 0.741 0.578 View mutations
382 L 0 19 19 0.995 0.730 View mutations
383 W 0 19 19 0.977 0.784 View mutations
384 T 16 3 19 0.209 0.287 View mutations
385 L 2 17 19 0.882 0.697 View mutations
386 R 0 19 19 1.000 0.862 View mutations
387 N 0 19 19 1.000 0.893 View mutations
388 L 5 14 19 0.727 0.647 View mutations
389 S 0 19 19 0.996 0.810 View mutations
390 D 1 18 19 0.937 0.768 View mutations
391 A 9 10 19 0.577 0.511 View mutations
392 A 17 2 19 0.174 0.409 View mutations
393 T 11 8 19 0.419 0.495 View mutations
394 K 16 3 19 0.145 0.482 View mutations
395 Q 19 0 19 0.000 0.458 View mutations
396 E 16 3 19 0.204 0.385 View mutations
397 G 12 7 19 0.374 0.462 View mutations
398 M 13 6 19 0.324 0.404 View mutations
399 E 17 2 19 0.084 0.442 View mutations
400 G 18 1 19 0.067 0.512 View mutations